ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
FDA AMDAC – Developing Single-Pathogen agents for P. aeruginosa and A. baumannii
The 37,000-year view: Infections in Eurasia
Draft FDA guidance on anti-infectives for children: It’s (mostly) all about PK and safety
Developing systemic & inhaled antibiotics for lung infections
How hard (and how) to Pull? Net value of Pull via a Transferrable Exclusivity Extension (TEE)
Chemical vs. drugs (Part 2): How do you discriminate? / More on halicin
Assessing antibiotic value: DTR, fire extinguishers, and a view from Australia
Mirror Bacteria: An AMR threat of unprecedented magnitude
The 6 meanings of “Lack of Access” (UNSLAP)
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
What does an antibiotic cost to develop? What is it worth? How to afford it?
News from Davos 2020: Some positive signs, but overall a fragile antibiotic market at a tipping point
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet